Synthesis and Characteristics of High-performance Mo Adsorbent for 99mTc Generators†

Yoshio HASEGAWA*, Mizuka NISHINO, Koji ISHIKAWA††, Katsuyoshi TATENUMA††, Masakazu TANASE††† and Kiyoyuki KUROSAWA††††

Functional Materials Institute, KAKEN Co.; Shikada, Asahi-mura, Kashima-gun, Ibaraki 311-1416 Japan
†† Mito Institute, KAKEN Co.; Hori, Mito-shi 310-0903 Japan
††† Advanced Science Research Center, Japan Atomic Energy Research Institute; Tokai-mura, Naka-gun, Ibaraki 319-1195 Japan
†††† Department of Radioisotopes, Japan Atomic Energy Research Institute; Tokai-mura, Naka-gun, Ibaraki 319-1195 Japan

To further increase the Mo adsorbing capacity of Mo adsorbent (hereinafter abbreviated as PZC) which are synthesized by using zirconium tetrachloride (ZrCl4) and isopropyl alcohol, the chlorine atom concentration was increased in the PZC. As a result, the Mo adsorbing capacity of the PZC was found to increase from the conventional 200 mg to 250 mg/g-PZC. Since the PZC adsorption capacity depends on the ratio of adjacent chlorine atoms in the PZC molecules, the mechanism with which the PZC adsorbs the Mo is thought to be one of chemical adsorption backed by chemical reaction between the two adjacent Zr-Cl bonds and MoO42−. Since the PZC having high Mo adsorption shows more adsorption than an estimated value, the effect of Mo polyions cannot be ignored.
The 99mTc elution yield of the Generator was measured using the PZC which adsorb Mo including 1 to 470 MBq 99Mo. The PZC was filled within a glass column with glass filter. The elution yield was found to be stable in the values ranging from 75--90% in each case. No increases in break-through of 99Mo were observed even by adsorbing 99Mo at 470 MBq, thereby it suggests that the PZC is kept stable, not being decomposed even under the condition of high radioactivity.
† Synthesis of Inorganic Polymers as Ion Exchanger. Part 2.


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